Chandy C John Selected Research

Angiopoietin-2

10/2022	Intestinal Injury Biomarkers Predict Mortality in Pediatric Severe Malaria.
11/2021	Decreased parasite burden and altered host response in children with sickle cell anemia and severe anemia with malaria.
1/2021	Plasma angiopoietin-2 is associated with age-related deficits in cognitive sub-scales in Ugandan children following severe malaria.
1/2020	Endothelial Activation, Acute Kidney Injury, and Cognitive Impairment in Pediatric Severe Malaria.
9/2016	Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria.
7/2011	Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial.

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Chandy C John Research Topics

Disease

98	Malaria 01/2024 - 04/2002
33	Cerebral Malaria 11/2023 - 09/2006
29	Infections 04/2024 - 08/2003
20	Anemia 11/2023 - 09/2004
14	Sickle Cell Anemia (Hemoglobin S Disease) 01/2024 - 06/2016
14	Inflammation (Inflammations) 11/2021 - 07/2011
10	Acute Kidney Injury (Acute Renal Failure) 12/2023 - 10/2016
8	Parasitemia 03/2024 - 03/2012
8	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2023 - 03/2008
7	Fever (Fevers) 10/2020 - 04/2014
6	Acidosis 01/2023 - 11/2016
6	Coma (Comas) 01/2023 - 01/2015
5	Cognitive Dysfunction 11/2023 - 09/2006
5	Hemolysis 01/2020 - 04/2016
5	Iron Deficiencies 01/2020 - 09/2014
4	COVID-19 01/2023 - 10/2020
3	Brain Injuries (Brain Injury) 01/2023 - 09/2006
3	Kidney Diseases (Kidney Disease) 10/2022 - 01/2022
3	Neurologic Manifestations (Neurological Manifestations) 01/2021 - 02/2008
3	Thrombocytopenia (Thrombopenia) 10/2020 - 07/2015
3	Communicable Diseases (Infectious Diseases) 01/2017 - 03/2008
3	Reinfection 07/2013 - 04/2002
2	Bacteremia 01/2024 - 12/2020
2	Stroke (Strokes) 07/2023 - 01/2020
2	Jaundice (Icterus) 01/2023 - 01/2023
2	Seizures (Absence Seizure) 01/2023 - 01/2020
2	Malnutrition (Nutritional Deficiencies) 10/2021 - 10/2017
2	Severe Acute Malnutrition 12/2020 - 01/2019
2	HIV Infections (HIV Infection) 12/2020 - 08/2019
2	Critical Illness (Critically Ill) 10/2020 - 11/2016
2	Bites and Stings (Sting) 01/2019 - 10/2009
2	Central Nervous System Infections (Central Nervous System Infection) 01/2017 - 02/2008

Drug/Important Bio-Agent (IBA)

23	AntigensIBA 12/2020 - 08/2003
21	AntibodiesIBA 01/2023 - 08/2003
18	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2009
15	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2004
14	Hemoglobins (Hemoglobin)IBA 01/2023 - 02/2008
12	Immunoglobulin G (IgG)IBA 01/2022 - 04/2002
11	CytokinesIBA 03/2024 - 09/2006
10	VaccinesIBA 01/2023 - 07/2004
9	Antimalarials (Antimalarial Agents)IBA 01/2020 - 07/2011
8	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2024 - 06/2016
8	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2023 - 07/2011
8	IronIBA 01/2022 - 09/2014
8	Merozoite Surface Protein 1 (MSA1)IBA 01/2017 - 11/2003
7	EnzymesIBA 01/2023 - 07/2004
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2021 - 09/2006
7	Interleukin-10 (Interleukin 10)IBA 01/2020 - 04/2006
7	ThrombospondinsIBA 01/2017 - 09/2004
6	Angiopoietin-2IBA 10/2022 - 07/2011
6	InterferonsIBA 01/2017 - 09/2006
6	Interferon-gamma (Interferon, gamma)IBA 01/2016 - 11/2003
5	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2024 - 12/2009
5	ArtesunateIBA 10/2022 - 07/2015
5	Immunoglobulin M (IgM)IBA 01/2021 - 07/2005
5	ChemokinesIBA 07/2015 - 09/2006
5	ImmunosorbentsIBA 10/2014 - 09/2004
4	piperaquineIBA 01/2024 - 11/2018
4	artenimol (dihydroartemisinin)IBA 01/2024 - 11/2018
4	artemisinin (artemisinine)IBA 01/2021 - 12/2009
4	Heme (Haem)IBA 01/2020 - 10/2016
4	Peptides (Polypeptides)IBA 10/2013 - 04/2002
3	pyrimethamine drug combination fanasil (Fansidar)FDA Link 01/2024 - 09/2004
3	DNA (Deoxyribonucleic Acid)IBA 11/2022 - 10/2019
3	CreatinineIBA 10/2022 - 01/2020
3	C-Reactive ProteinIBA 12/2020 - 09/2014
3	Ferritins (Ferritin)IBA 12/2020 - 09/2014
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2020 - 03/2012
3	Chemokine CCL5IBA 07/2015 - 09/2006
3	Interleukin-6 (Interleukin 6)IBA 07/2015 - 09/2006
2	Nucleic AcidsIBA 04/2024 - 01/2021
2	ZincIBA 07/2023 - 07/2019
2	NitrogenIBA 01/2023 - 10/2022
2	KynurenineIBA 01/2023 - 01/2017
2	PhosphatidylserinesIBA 01/2023 - 10/2019
2	Urea (Carbamide)FDA LinkGeneric 01/2023 - 10/2022
2	Vitamin D FDA LinkGeneric 01/2022 - 01/2014
2	Sickle HemoglobinIBA 11/2021 - 07/2013
2	MicronutrientsIBA 12/2020 - 10/2017
2	von Willebrand FactorIBA 01/2020 - 03/2012
2	zinc protoporphyrinIBA 01/2020 - 01/2017
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2020 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 04/2014
2	Transferrin Receptors (Transferrin Receptor)IBA 01/2020 - 09/2014
2	Kynurenic Acid (Kynurenate)IBA 01/2020 - 01/2017
2	Immunoglobulins (Immunoglobulin)IBA 08/2019 - 02/2015
2	Endothelial Protein C ReceptorIBA 10/2017 - 01/2016
2	insulin receptor-related receptor (IRR)IBA 09/2017 - 01/2017
2	Histidine (L-Histidine)FDA Link 01/2017 - 08/2012
2	Lactic Acid (Lactate)FDA LinkGeneric 11/2016 - 04/2014
2	Malaria VaccinesIBA 10/2015 - 07/2004
2	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2012 - 04/2010

Therapy/Procedure

22	Therapeutics 01/2023 - 08/2006
7	Chemoprevention 01/2024 - 11/2018
4	Blood Transfusion (Blood Transfusions) 01/2018 - 01/2016
3	Aftercare (After-Treatment) 10/2022 - 09/2004
3	Cognitive Training 08/2011 - 09/2006
2	Patient Readmission 10/2021 - 10/2019
2	Treatment Delay 10/2020 - 01/2020
2	Ambulatory Care (Outpatient Care) 09/2017 - 01/2017